1WQJ
Structural Basis for the Regulation of Insulin-Like Growth Factors (IGFs) by IGF Binding Proteins (IGFBPs)
Summary for 1WQJ
Entry DOI | 10.2210/pdb1wqj/pdb |
Related | 1H59 |
Descriptor | Insulin-like growth factor binding protein 4, Insulin-like growth factor IB (3 entities in total) |
Functional Keywords | protein-protein complex, disulfide rich, disulfide bond ladder, protein binding-hormone-growth factor complex, protein binding/hormone/growth factor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P22692 P05019 |
Total number of polymer chains | 2 |
Total formula weight | 16161.87 |
Authors | Siwanowicz, I.,Popowicz, G.M.,Wisniewska, M.,Huber, R.,Kuenkele, K.P.,Lang, K.,Engh, R.A.,Holak, T.A. (deposition date: 2004-09-29, release date: 2005-03-01, Last modification date: 2023-10-25) |
Primary citation | Siwanowicz, I.,Popowicz, G.M.,Wisniewska, M.,Huber, R.,Kuenkele, K.P.,Lang, K.,Engh, R.A.,Holak, T.A. Structural basis for the regulation of insulin-like growth factors by IGF binding proteins Structure, 13:155-167, 2005 Cited by PubMed: 15642270DOI: 10.1016/j.str.2004.11.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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