1WER
RAS-GTPASE-ACTIVATING DOMAIN OF HUMAN P120GAP
Summary for 1WER
Entry DOI | 10.2210/pdb1wer/pdb |
Descriptor | P120GAP (2 entities in total) |
Functional Keywords | gtpase activation, ras, gap, signal transduction, growth regulation, cancer |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P20936 |
Total number of polymer chains | 1 |
Total formula weight | 38223.28 |
Authors | Scheffzek, K.,Lautwein, A.,Kabsch, W.,Ahmadian, M.R.,Wittinghofer, A. (deposition date: 1996-11-20, release date: 1997-12-31, Last modification date: 2024-02-14) |
Primary citation | Scheffzek, K.,Lautwein, A.,Kabsch, W.,Ahmadian, M.R.,Wittinghofer, A. Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras. Nature, 384:591-596, 1996 Cited by PubMed: 8955277DOI: 10.1038/384591a0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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