1WB0
specificity and affinity of natural product cyclopentapeptide inhibitor Argifin against human chitinase
Summary for 1WB0
Entry DOI | 10.2210/pdb1wb0/pdb |
Related | 1GUV 1HKI 1HKJ 1HKK 1HKM 1LG1 1LG2 1LQ0 1WAW |
Related PRD ID | PRD_000465 |
Descriptor | CHITOTRIOSIDASE 1, ARGIFIN, ISOPROPYL ALCOHOL, ... (6 entities in total) |
Functional Keywords | cyclopentapeptide inhibitors, chitinase inhibitors, carbohydrate metabolism, chitin degradation, chitin-binding, glycosidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted: Q13231 |
Total number of polymer chains | 2 |
Total formula weight | 50654.39 |
Authors | Rao, F.V.,Houston, D.R.,Boot, R.G.,Aerts, J.M.F.G.,Hodkinson, M.,Adams, D.J.,Shiomi, K.,Omura, S.,Van Aalten, D.M.F. (deposition date: 2004-10-29, release date: 2005-01-28, Last modification date: 2023-12-13) |
Primary citation | Rao, F.V.,Houston, D.R.,Boot, R.G.,Aerts, J.M.F.G.,Hodkinson, M.,Adams, D.J.,Shiomi, K.,Omura, S.,Van Aalten, D.M.F. Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases Chem.Biol., 12:65-, 2005 Cited by PubMed: 15664516DOI: 10.1016/J.CHEMBIOL.2004.10.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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