1W2N

Deacetoxycephalosporin C synthase (with a N-terminal his-tag) in complex with Fe(II) and ampicillin

Summary for 1W2N

Entry DOI	10.2210/pdb1w2n/pdb
Descriptor	DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (III) ION, (2S,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, ... (4 entities in total)
Functional Keywords	oxidoreductase, cephalosporin, penicillin, mononuclear ferrous enzymes, 2-oxoglutarate dependent oxygenases, antibiotic biosynthesis
Biological source	STREPTOMYCES CLAVULIGERUS
Total number of polymer chains	1
Total formula weight	37168.25
Authors	Oster, L.M.,Terwisscha Van Scheltinga, A.C.,Valegard, K.,Mackenzie Hose, A.,Dubus, A.,Hajdu, J.,Andersson, I. (deposition date: 2004-07-07, release date: 2004-09-30, Last modification date: 2011-07-13)
Primary citation	Oster, L.M.,Terwisscha Van Scheltinga, A.C.,Valegard, K.,Mackenzie Hose, A.,Dubus, A.,Hajdu, J.,Andersson, I. Conformational Flexibility of the C Terminus with Implications for Substrate Binding and Catalysis Revealed in a New Crystal Form of Deacetoxycephalosporin C Synthase J.Mol.Biol., 343:157-, 2004 Cited by PubMed: 15381427 DOI: 10.1016/J.JMB.2004.07.049 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation