1VJA
Urokinase Plasminogen Activator B-Chain-JT463 Complex
Summary for 1VJA
Entry DOI | 10.2210/pdb1vja/pdb |
Related | 1F5K 1F5L 1F92 1SC8 1VJ9 |
Descriptor | plasminogen activator, urokinase, SULFATE ION, N-(BENZYLSULFONYL)SERYL-N~1~-{4-[(Z)-AMINO(IMINO)METHYL]BENZYL}SERINAMIDE, ... (4 entities in total) |
Functional Keywords | urokinase, inhibitor, serine protease, human, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P00749 |
Total number of polymer chains | 1 |
Total formula weight | 30353.61 |
Authors | Schweinitz, A.,Steinmetzer, T.,Banke, I.J.,Arlt, M.J.E.,Stuerzebecher, A.,Schuster, O.,Geissler, A.,Giersiefen, H.,Zeslawska, E.,Jacob, U.,Kruger, A.,Stuerzebecher, J. (deposition date: 2004-02-03, release date: 2004-06-22, Last modification date: 2023-08-23) |
Primary citation | Schweinitz, A.,Steinmetzer, T.,Banke, I.J.,Arlt, M.J.E.,Stuerzebecher, A.,Schuster, O.,Geissler, A.,Giersiefen, H.,Zeslawska, E.,Jacob, U.,Kruger, A.,Stuerzebecher, J. Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents J.Biol.Chem., 279:33613-33622, 2004 Cited by PubMed: 15150279DOI: 10.1074/jbc.M314151200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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