1VIE
STRUCTURE OF DIHYDROFOLATE REDUCTASE
Summary for 1VIE
Entry DOI | 10.2210/pdb1vie/pdb |
Descriptor | DIHYDROFOLATE REDUCTASE (2 entities in total) |
Functional Keywords | oxidoreductase, nadp, trimethoprim resistance, methotrexate resistance, one-carbon metabolism, plasmid |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 6732.53 |
Authors | Narayana, N.,Matthews, D.A.,Howell, E.E.,Xuong, N.-H. (deposition date: 1996-10-03, release date: 1997-10-22, Last modification date: 2024-02-14) |
Primary citation | Narayana, N.,Matthews, D.A.,Howell, E.E.,Nguyen-huu, X. A plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active site. Nat.Struct.Biol., 2:1018-1025, 1995 Cited by PubMed: 7583655DOI: 10.1038/nsb1195-1018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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