1V8K
The Crystal Structure of the Minimal Functional Domain of the Microtubule Destabilizer KIF2C Complexed with Mg-AMPPNP
Summary for 1V8K
Entry DOI | 10.2210/pdb1v8k/pdb |
Related | 1V8J |
Descriptor | Kinesin-like protein KIF2C, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total) |
Functional Keywords | kinesin-like protein, microtubule destabilizer, structural protein |
Biological source | Mus musculus (house mouse) |
Cellular location | Cytoplasm, cytoskeleton (By similarity): Q922S8 |
Total number of polymer chains | 1 |
Total formula weight | 47333.21 |
Authors | Ogawa, T.,Nitta, R.,Okada, Y.,Hirokawa, N. (deposition date: 2004-01-09, release date: 2004-03-02, Last modification date: 2023-12-27) |
Primary citation | Ogawa, T.,Nitta, R.,Okada, Y.,Hirokawa, N. A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops. Cell(Cambridge,Mass.), 116:591-602, 2004 Cited by PubMed: 14980225DOI: 10.1016/S0092-8674(04)00129-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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