1UUO

Rat dihydroorotate dehydrogenase (DHOD)in complex with brequinar

Summary for 1UUO

Entry DOI	10.2210/pdb1uuo/pdb
Related	1UUM
Descriptor	DIHYDROOROTATE DEHYDROGENASE, 6-FLUORO-2-(2'-FLUORO-1,1'-BIPHENYL-4-YL)-3-METHYLQUINOLINE-4-CARBOXYLIC ACID, FLAVIN MONONUCLEOTIDE, ... (7 entities in total)
Functional Keywords	dihydroorotate dehydrogenase, brequinar, atovaquone, nucleotide metabolism, oxidoreductase
Biological source	RATTUS RATTUS (BLACK RAT, ROOF RAT)
Total number of polymer chains	1
Total formula weight	41410.37
Authors	Hansen, M.,Le Nours, J.,Johansson, E.,Antal, T.,Ullrich, A.,Loffler, M.,Larsen, S. (deposition date: 2004-01-08, release date: 2004-04-01, Last modification date: 2019-01-30)
Primary citation	Hansen, M.,Le Nours, J.,Johansson, E.,Antal, T.,Ullrich, A.,Loffler, M.,Larsen, S. Inhibitor Binding in a Class 2 Dihydroorotate Dehydrogenase Causes Variations in the Membrane-Associated N-Terminal Domain Protein Sci., 13:1031-, 2004 Cited by PubMed: 15044733 DOI: 10.1110/PS.03533004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.44 Å)

Structure validation