1TTV
NMR Structure of a Complex Between MDM2 and a Small Molecule Inhibitor
Summary for 1TTV
Entry DOI | 10.2210/pdb1ttv/pdb |
Related | 1RV1 1YCQ |
NMR Information | BMRB: 6248 |
Descriptor | Ubiquitin-protein ligase E3 Mdm2, 1-{[4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]CARBONYL}PIPERAZINE (2 entities in total) |
Functional Keywords | mdm2, protein-protein interaction, ligase |
Biological source | Xenopus laevis (African clawed frog) |
Cellular location | Nucleus, nucleoplasm (By similarity): P56273 |
Total number of polymer chains | 1 |
Total formula weight | 12774.39 |
Authors | Fry, D.C.,Emerson, S.D.,Palme, S.,Vu, B.T.,Liu, C.M.,Podlaski, F. (deposition date: 2004-06-23, release date: 2005-01-04, Last modification date: 2024-05-22) |
Primary citation | Fry, D.C.,Emerson, S.D.,Palme, S.,Vu, B.T.,Liu, C.M.,Podlaski, F. NMR structure of a complex between MDM2 and a small molecule inhibitor. J.Biomol.Nmr, 30:163-173, 2004 Cited by PubMed: 15557803DOI: 10.1023/B:JNMR.0000048856.84603.9b PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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