1TTL
Omega-conotoxin GVIA, a N-type calcium channel blocker
Summary for 1TTL
Entry DOI | 10.2210/pdb1ttl/pdb |
Related | 1OMC 2CCO |
Descriptor | Omega-conotoxin GVIA (1 entity in total) |
Functional Keywords | disulfide rich, four loop framework, amidated c-terminal, toxin |
Biological source | Conus geographus (geography cone) |
Cellular location | Secreted: P01522 |
Total number of polymer chains | 1 |
Total formula weight | 3046.42 |
Authors | Mould, J.,Yasuda, T.,Schroeder, C.I.,Beedle, A.M.,Doering, C.J.,Zamponi, G.W.,Adams, D.J.,Lewis, R.J. (deposition date: 2004-06-23, release date: 2004-07-13, Last modification date: 2011-07-13) |
Primary citation | Mould, J.,Yasuda, T.,Schroeder, C.I.,Beedle, A.M.,Doering, C.J.,Zamponi, G.W.,Adams, D.J.,Lewis, R.J. The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels J.Biol.Chem., 279:34705-34714, 2004 Cited by PubMed: 15166237DOI: 10.1074/jbc.M310848200 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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