1TPX
Ovine recombinant PrP(114-234), ARQ variant in complex with the Fab of the VRQ14 antibody
Summary for 1TPX
Entry DOI | 10.2210/pdb1tpx/pdb |
Descriptor | major prion protein, the VRQ14 Fab, ... (4 entities in total) |
Functional Keywords | prion, antibody, unknown function |
Biological source | Ovis aries (sheep) More |
Total number of polymer chains | 3 |
Total formula weight | 60831.69 |
Authors | Eghiaian, F.,Grosclaude, J.,Lesceu, S.,Debey, P.,Doublet, B.,Treguer, E.,Rezaei, H.,Knossow, M. (deposition date: 2004-06-16, release date: 2004-07-06, Last modification date: 2011-07-13) |
Primary citation | Eghiaian, F.,Grosclaude, J.,Lesceu, S.,Debey, P.,Doublet, B.,Treguer, E.,Rezaei, H.,Knossow, M. Insight into the PrPC -> PrPSc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants. Proc.Natl.Acad.Sci.USA, 101:10254-10259, 2004 Cited by PubMed: 15240887DOI: 10.1073/pnas.0400014101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.56 Å) |
Structure validation
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