1TOW
Crystal structure of human adipocyte fatty acid binding protein in complex with a carboxylic acid ligand
Summary for 1TOW
Entry DOI | 10.2210/pdb1tow/pdb |
Related | 1TOU |
Descriptor | Fatty acid-binding protein, adipocyte, 4-(9H-CARBAZOL-9-YL)BUTANOIC ACID (3 entities in total) |
Functional Keywords | transport, lipid-binding, lipid transport |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P15090 |
Total number of polymer chains | 1 |
Total formula weight | 14862.00 |
Authors | Lehmann, F.,Haile, S.,Axen, E.,Medina, C.,Uppenberg, J.,Svensson, S.,Lundback, T.,Rondahl, L.,Barf, T. (deposition date: 2004-06-15, release date: 2004-08-24, Last modification date: 2024-03-13) |
Primary citation | Lehmann, F.,Haile, S.,Axen, E.,Medina, C.,Uppenberg, J.,Svensson, S.,Lundback, T.,Rondahl, L.,Barf, T. Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target. Bioorg.Med.Chem.Lett., 14:4445-4448, 2004 Cited by PubMed: 15357969DOI: 10.1016/j.bmcl.2004.06.057 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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