1TK0
T7 DNA polymerase ternary complex with 8 oxo guanosine and ddCTP at the insertion site
Summary for 1TK0
Entry DOI | 10.2210/pdb1tk0/pdb |
Related | 1T8E |
Descriptor | 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*A*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DDG))-3', 5'-D(*CP*CP*CP*(8OG)P*CP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', DNA polymerase, ... (10 entities in total) |
Functional Keywords | 8 oxo guanosine, dna polymerase, transferase-electron transport-dna complex, transferase/electron transport/dna |
Biological source | Enterobacteria phage T7 More |
Total number of polymer chains | 4 |
Total formula weight | 106630.35 |
Authors | Brieba, L.G.,Eichman, B.F.,Kokoska, R.J.,Doublie, S.,Kunkel, T.A.,Ellenberger, T. (deposition date: 2004-06-07, release date: 2004-08-31, Last modification date: 2023-08-23) |
Primary citation | Brieba, L.G.,Eichman, B.F.,Kokoska, R.J.,Doublie, S.,Kunkel, T.A.,Ellenberger, T. Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Embo J., 23:3452-3461, 2004 Cited by PubMed: 15297882DOI: 10.1038/sj.emboj.7600354 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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