1TCE

SOLUTION NMR STRUCTURE OF THE SHC SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM THE T-CELL RECEPTOR, MINIMIZED AVERAGE STRUCTURE

Summary for 1TCE

Entry DOI	10.2210/pdb1tce/pdb
Descriptor	SHC, PHOSPHOPEPTIDE OF THE ZETA CHAIN OF T CELL RECEPTOR (2 entities in total)
Functional Keywords	sh2 domain, complex (signal transduction-peptide), complex (signal transduction-peptide) complex, complex (signal transduction/peptide)
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm. Isoform p46Shc: Mitochondrion matrix. Isoform p66Shc: Mitochondrion (By similarity): P29353 Membrane; Single-pass type I membrane protein: P20963
Total number of polymer chains	2
Total formula weight	13653.22
Authors	Zhou, M.-M.,Meadows, R.P.,Logan, T.M.,Yoon, H.S.,Wade, W.R.,Ravichandran, K.S.,Burakoff, S.J.,Feisk, S.W. (deposition date: 1996-03-27, release date: 1997-05-15, Last modification date: 2022-03-02)
Primary citation	Zhou, M.M.,Meadows, R.P.,Logan, T.M.,Yoon, H.S.,Wade, W.S.,Ravichandran, K.S.,Burakoff, S.J.,Fesik, S.W. Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor. Proc.Natl.Acad.Sci.USA, 92:7784-7788, 1995 Cited by PubMed: 7544002 DOI: 10.1073/pnas.92.17.7784 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation