1T7D
Crystal structure of Escherichia coli type I signal peptidase in complex with a lipopeptide inhibitor
Summary for 1T7D
Entry DOI | 10.2210/pdb1t7d/pdb |
Related | 1B12 1KN9 3IIQ |
Related PRD ID | PRD_000117 |
Descriptor | SIGNAL PEPTIDASE I, ARYLOMYCIN A2, 10-METHYLUNDECANOIC ACID, ... (4 entities in total) |
Functional Keywords | signal peptidase, ser/lys dyad, hydrolase, lipopeptide, antibiotic, biaryl bridge, hydrolase-antibiotic complex, hydrolase/antibiotic |
Biological source | ESCHERICHIA COLI More |
Cellular location | Cell inner membrane; Multi-pass membrane protein: P00803 |
Total number of polymer chains | 4 |
Total formula weight | 57849.61 |
Authors | Paetzel, M.,Goodall, J.J.,Kania, M.,Dalbey, R.E.,Page, M.G.P. (deposition date: 2004-05-09, release date: 2004-07-13, Last modification date: 2023-08-23) |
Primary citation | Paetzel, M.,Goodall, J.J.,Kania, M.,Dalbey, R.E.,Page, M.G.P. Crystallographic and Biophysical Analysis of a Bacterial Signal Peptidase in Complex with a Lipopeptide Based Inhibitor. J.Biol.Chem., 279:30781-, 2004 Cited by PubMed: 15136583DOI: 10.1074/JBC.M401686200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.47 Å) |
Structure validation
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