1T0M
Conformational switch in polymorphic H-2K molecules containing an HSV peptide
Summary for 1T0M
Entry DOI | 10.2210/pdb1t0m/pdb |
Related | 1T0N |
Descriptor | H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, Glycoprotein B, ... (4 entities in total) |
Functional Keywords | immunoglobulin domain, mhc class i alpha domains, hsv peptide, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 6 |
Total formula weight | 89392.36 |
Authors | Webb, A.I.,Borg, N.A.,Dunstone, M.A.,Kjer-Nielsen, L.,Beddoe, T.,McCluskey, J.,Carbone, F.R.,Bottomley, S.P.,Purcell, A.W.,Rossjohn, J. (deposition date: 2004-04-12, release date: 2004-11-23, Last modification date: 2019-11-06) |
Primary citation | Webb, A.I.,Borg, N.A.,Dunstone, M.A.,Kjer-Nielsen, L.,Beddoe, T.,McCluskey, J.,Carbone, F.R.,Bottomley, S.P.,Aguilar, M.I.,Purcell, A.W.,Rossjohn, J. The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance. J Immunol., 173:402-409, 2004 Cited by PubMed: 15210799DOI: 10.4049/jimmunol.173.1.402 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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