1SXJ
Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA Sliding Clamp (Proliferating Cell Nuclear Antigen, PCNA)
Summary for 1SXJ
Entry DOI | 10.2210/pdb1sxj/pdb |
Related | 1PLQ |
Descriptor | Activator 1 95 kDa subunit, Activator 1 37 kDa subunit, Activator 1 40 kDa subunit, ... (9 entities in total) |
Functional Keywords | clamp loader, processivity clamp, dna sliding clamp, aaa+ atpase, dna polymerase, dna-binding protein, replication |
Biological source | Saccharomyces cerevisiae (baker's yeast) More |
Cellular location | Nucleus (Probable): P38630 P40339 P38629 P40348 P38251 Nucleus: P15873 |
Total number of polymer chains | 8 |
Total formula weight | 309282.41 |
Authors | Bowman, G.D.,O'Donnell, M.,Kuriyan, J. (deposition date: 2004-03-30, release date: 2004-06-22, Last modification date: 2023-11-15) |
Primary citation | Bowman, G.D.,O'Donnell, M.,Kuriyan, J. Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex. Nature, 429:724-730, 2004 Cited by PubMed: 15201901DOI: 10.1038/nature02585 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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