1SNX
CRYSTAL STRUCTURE OF APO INTERLEUKIN-2 TYROSINE KINASE CATALYTIC DOMAIN
Summary for 1SNX
Entry DOI | 10.2210/pdb1snx/pdb |
Related | 1SM2 1SNU |
Descriptor | Tyrosine-protein kinase ITK/TSK (1 entity in total) |
Functional Keywords | protein kinase, immunology, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane (By similarity): Q08881 |
Total number of polymer chains | 2 |
Total formula weight | 60208.85 |
Authors | Brown, K.,Long, J.M.,Vial, S.C.,Dedi, N.,Dunster, N.J.,Renwick, S.B.,Tanner, A.J.,Frantz, J.D.,Fleming, M.A.,Cheetham, G.M.T. (deposition date: 2004-03-12, release date: 2004-07-20, Last modification date: 2024-04-03) |
Primary citation | Brown, K.,Long, J.M.,Vial, S.C.,Dedi, N.,Dunster, N.J.,Renwick, S.B.,Tanner, A.J.,Frantz, J.D.,Fleming, M.A.,Cheetham, G.M. Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors. J.Biol.Chem., 279:18727-18732, 2004 Cited by PubMed: 14766749DOI: 10.1074/jbc.M400031200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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