1SHW

EphB2 / EphrinA5 Complex Structure

Summary for 1SHW

• Entry DOI: 10.2210/pdb1shw/pdb
• Related: 1NUK 1SHX
• Related PRD ID: PRD_900017
• Descriptor: Ephrin-A5, Ephrin type-B receptor 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: receptor tyrosine kinase, ephrin signaling, hormone-growth factor-receptor complex, hormone/growth factor/receptor
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 37897.90

Authors

Himanen, J.P.,Chumley, M.J.,Lackmann, M.,Li, C.,Barton, W.A.,Jeffrey, P.D.,Vearing, C.,Geleick, D.,Feldheim, D.A.,Boyd, A.W. (deposition date: 2004-02-26, release date: 2004-05-18, Last modification date: 2024-04-03)

• Primary citation: Himanen, J.P.,Chumley, M.J.,Lackmann, M.,Li, C.,Barton, W.A.,Jeffrey, P.D.,Vearing, C.,Geleick, D.,Feldheim, D.A.,Boyd, A.W.,Henkemeyer, M.,Nikolov, D.B.; Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling; Nat.Neurosci., 7:501-509, 2004; PubMed: 15107857; DOI: 10.1038/nn1237

Experimental method

X-RAY DIFFRACTION (2.2 Å)