1SHJ
Caspase-7 in complex with DICA allosteric inhibitor
Summary for 1SHJ
Entry DOI | 10.2210/pdb1shj/pdb |
Related | 1SHL |
Descriptor | Caspase-7, SULFATE ION, 2-(2,4-DICHLORO-PHENOXY)-N-(2-MERCAPTO-ETHYL)-ACETAMIDE (3 entities in total) |
Functional Keywords | cysteine protease, allosteric, inhibitor, central cavity, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P55210 |
Total number of polymer chains | 2 |
Total formula weight | 60730.51 |
Authors | Hardy, J.A.,Lam, J.,Nguyen, J.T.,O'Brien, T.,Wells, J.A. (deposition date: 2004-02-25, release date: 2004-08-17, Last modification date: 2023-08-23) |
Primary citation | Hardy, J.A.,Lam, J.,Nguyen, J.T.,O'Brien, T.,Wells, J.A. Discovery of an allosteric site in the caspases Proc.Natl.Acad.Sci.USA, 101:12461-12466, 2004 Cited by PubMed: 15314233DOI: 10.1073/pnas.0404781101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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