1S7G
Structural Basis for the Mechanism and Regulation of Sir2 Enzymes
Summary for 1S7G
Entry DOI | 10.2210/pdb1s7g/pdb |
Descriptor | NAD-dependent deacetylase 2, ADENOSINE-5-DIPHOSPHORIBOSE, ZINC ION, ... (11 entities in total) |
Functional Keywords | enzyme, sirtuin, sir2, nad+, adp-ribose, transcription |
Biological source | Archaeoglobus fulgidus |
Cellular location | Cytoplasm (Probable): O30124 |
Total number of polymer chains | 5 |
Total formula weight | 148485.81 |
Authors | Avalos, J.L.,Boeke, J.D.,Wolberger, C. (deposition date: 2004-01-29, release date: 2004-03-23, Last modification date: 2023-08-23) |
Primary citation | Avalos, J.L.,Boeke, J.D.,Wolberger, C. Structural basis for the mechanism and regulation of sir2 enzymes Mol.Cell, 13:639-648, 2004 Cited by PubMed: 15023335DOI: 10.1016/S1097-2765(04)00082-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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