1RZ8
CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 17B
Summary for 1RZ8
Entry DOI | 10.2210/pdb1rz8/pdb |
Related | 1RZ7 1RZF 1RZG 1RZI 1RZJ 1RZK |
Descriptor | Fab 17b light chain, Fab 17b heavy chain (3 entities in total) |
Functional Keywords | hiv-1; gp120; cd4i; antibodies; tyrosine sulfation; vh-gene usage, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 95456.21 |
Authors | Huang, C.C.,Venturi, M.,Majeed, S.,Moore, M.J.,Phogat, S.,Zhang, M.-Y.,Dimitrov, D.S.,Hendrickson, W.A.,Robinson, J.,Sodroski, J.,Wyatt, R.,Choe, H.,Farzan, M.,Kwong, P.D. (deposition date: 2003-12-24, release date: 2004-02-03, Last modification date: 2023-08-23) |
Primary citation | Huang, C.C.,Venturi, M.,Majeed, S.,Moore, M.J.,Phogat, S.,Zhang, M.-Y.,Dimitrov, D.S.,Hendrickson, W.A.,Robinson, J.,Sodroski, J.,Wyatt, R.,Choe, H.,Farzan, M.,Kwong, P.D. Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101:2706-2711, 2004 Cited by PubMed: 14981267DOI: 10.1073/pnas.0308527100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report