1RTJ

MECHANISM OF INHIBITION OF HIV-1 REVERSE TRANSCRIPTASE BY NON-NUCLEOSIDE INHIBITORS

Summary for 1RTJ

Entry DOI	10.2210/pdb1rtj/pdb
Descriptor	HIV-1 REVERSE TRANSCRIPTASE (3 entities in total)
Functional Keywords	hiv-1 reverse transcriptase, nucleotidyltransferase
Biological source	Human immunodeficiency virus 1 More
Cellular location	Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P04585 P04585
Total number of polymer chains	2
Total formula weight	115994.00
Authors	Ren, J.,Esnouf, R.,Ross, C.,Jones, Y.,Stammers, D.,Stuart, D. (deposition date: 1995-05-03, release date: 1996-04-03, Last modification date: 2011-07-13)
Primary citation	Esnouf, R.,Ren, J.,Ross, C.,Jones, Y.,Stammers, D.,Stuart, D. Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors. Nat.Struct.Biol., 2:303-308, 1995 Cited by PubMed: 7540935 DOI: 10.1038/nsb0495-303 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation