1RJC

Crystal structure of the camelid single domain antibody cAb-Lys2 in complex with hen egg white lysozyme

Summary for 1RJC

• Entry DOI: 10.2210/pdb1rjc/pdb
• Related: 1RI8
• Descriptor: camelid heavy chain antibody, Lysozyme C, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: beta sandwich, immunoglobulin fold, protein-protein hetero complex, alpha-beta orthogonal bundle, immune system-hydrolase complex, immune system/hydrolase
• Biological source: Camelus dromedarius (Arabian camel); More
• Cellular location: Secreted: P00698
• Total number of polymer chains: 2
• Total formula weight: 29420.52

Authors

De Genst, E.,Silence, K.,Ghahroudi, M.A.,Decanniere, K.,Loris, R.,Kinne, J.,Wyns, L.,Muyldermans, S. (deposition date: 2003-11-19, release date: 2005-02-01, Last modification date: 2011-07-13)

• Primary citation: De Genst, E.,Silence, K.,Ghahroudi, M.A.,Decanniere, K.,Loris, R.,Kinne, J.,Wyns, L.,Muyldermans, S.; Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.; J.Biol.Chem., 280:14114-14121, 2005; PubMed: 15659390; DOI: 10.1074/jbc.M413011200

Experimental method

X-RAY DIFFRACTION (1.4 Å)