1R2G
Human Bcl-XL containing a Phe to Trp mutation at position 97
Summary for 1R2G
Entry DOI | 10.2210/pdb1r2g/pdb |
Related | 1MAZ 1R2D 1R2E 1R2H 1R2I |
Descriptor | Apoptosis regulator Bcl-X (2 entities in total) |
Functional Keywords | apoptosis, monomeric, alpha-helical, mutation |
Biological source | Homo sapiens (human) |
Cellular location | Isoform Bcl-X(L): Mitochondrion inner membrane : Q07817 |
Total number of polymer chains | 1 |
Total formula weight | 24645.97 |
Authors | O'Neill, J.W.,Manion, M.K.,Giedt, C.D.,Kim, K.M.,Zhang, K.Y.,Hockenbery, D.M. (deposition date: 2003-09-26, release date: 2004-02-03, Last modification date: 2023-08-23) |
Primary citation | Manion, M.K.,O'Neill, J.W.,Giedt, C.D.,Kim, K.M.,Zhang, K.Y.,Hockenbery, D.M. Bcl-XL mutations suppress cellular sensitivity to antimycin A. J.Biol.Chem., 279:2159-2165, 2004 Cited by PubMed: 14534311DOI: 10.1074/jbc.M306021200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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