1R1K

Crystal structure of the ligand-binding domains of the heterodimer EcR/USP bound to ponasterone A

Summary for 1R1K

• Entry DOI: 10.2210/pdb1r1k/pdb
• Related: 1R20
• Descriptor: Ecdysone receptor, ULTRASPIRACLE PROTEIN, 2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE, ... (5 entities in total)
• Functional Keywords: nuclear receptor, transcription regulation, heterodimer, alpha-helical sandwich, structural proteomics in europe, spine, structural genomics, hormone-growth factor receptor complex, hormone/growth factor receptor
• Biological source: Heliothis virescens (tobacco budworm); More
• Cellular location: Nucleus: O18473
• Total number of polymer chains: 2
• Total formula weight: 61495.29

Authors

Billas, I.M.L.,Iwema, T.,Garnier, J.-M.,Mitschler, A.,Rochel, N.,Moras, D.,Structural Proteomics in Europe (SPINE) (deposition date: 2003-09-24, release date: 2003-11-18, Last modification date: 2023-08-23)

• Primary citation: Billas, I.M.L.,Iwema, T.,Garnier, J.M.,Mitschler, A.,Rochel, N.,Moras, D.; Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor.; Nature, 426:91-96, 2003; PubMed: 14595375; DOI: 10.1038/nature02112

Experimental method

X-RAY DIFFRACTION (2.9 Å)