1QBN

Bovine Trypsin 2-[amino(imino)methyl]-2-hydroxyphenoxy]-6-[3-(4,5-dihydro-1H-imidazol-2-yl)phenoxy]pyridine-4-carboxylic Acid (ZK-806688) Complex

Summary for 1QBN

• Entry DOI: 10.2210/pdb1qbn/pdb
• Related: 1QA0
• Descriptor: PROTEIN (TRYPSIN), CALCIUM ION, 2-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-6-[3-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)PHENOXY]PYRIDINE-4-CARBOXYLIC ACID, ... (4 entities in total)
• Functional Keywords: hydrolase, serine proteinase, protein-inhibitor complex, s1 pocket
• Biological source: Bos taurus (cattle)
• Cellular location: Secreted, extracellular space: P00760
• Total number of polymer chains: 1
• Total formula weight: 23835.84

Authors

Whitlow, M. (deposition date: 1999-04-25, release date: 2000-05-03, Last modification date: 2011-07-13)

• Primary citation: Whitlow, M.,Arnaiz, D.O.,Buckman, B.O.,Davey, D.D.,Griedel, B.,Guilford, W.J.,Koovakkat, S.K.,Liang, A.,Mohan, R.,Phillips, G.B.,Seto, M.,Shaw, K.J.,Xu, W.,Zhao, Z.,Light, D.R.,Morrissey, M.M.; Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin.; Acta Crystallogr.,Sect.D, 55:1395-1404, 1999; PubMed: 10417407; DOI: 10.1107/S0907444999007350

Experimental method

X-RAY DIFFRACTION (1.8 Å)