1Q61

PKA triple mutant model of PKB

Summary for 1Q61

• Entry DOI: 10.2210/pdb1q61/pdb
• Related: 1CDK 1Q24 1Q62
• Descriptor: cAMP-dependent protein kinase, alpha-catalytic subunit, cAMP-dependent protein kinase inhibitor, alpha form, N-OCTANOYL-N-METHYLGLUCAMINE, ... (4 entities in total)
• Functional Keywords: pkb-model, restoration of atp-site, point mutation, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Bos taurus (cattle); More
• Cellular location: Cytoplasm: P00517
• Total number of polymer chains: 2
• Total formula weight: 43245.27

Authors

Gassel, M.,Breitenlechner, C.B.,Rueger, P.,Jucknischke, U.,Schneider, T.,Huber, R.,Bossemeyer, D.,Engh, R.A. (deposition date: 2003-08-12, release date: 2003-09-30, Last modification date: 2021-10-27)

• Primary citation: Gassel, M.,Breitenlechner, C.B.,Rueger, P.,Jucknischke, U.,Schneider, T.,Huber, R.,Bossemeyer, D.,Engh, R.A.; Mutants of protein kinase A that mimic the ATP-binding site of protein kinase B (AKT); J.Mol.Biol., 329:1021-1034, 2003; PubMed: 12798691; DOI: 10.1016/S0022-2836(03)00518-7

Experimental method

X-RAY DIFFRACTION (2.1 Å)