1Q43
HCN2I 443-640 in the presence of cAMP, selenomethionine derivative
Summary for 1Q43
Entry DOI | 10.2210/pdb1q43/pdb |
Related | 1Q3E 1Q5O |
Descriptor | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total) |
Functional Keywords | cnbd, c-linker, pacemaker, hcn, hcn2, channel, cyclic nucleotide, cap, pka, camp, ion channel, ligand, transport protein |
Biological source | Mus musculus (house mouse) |
Cellular location | Membrane; Multi-pass membrane protein: O88703 |
Total number of polymer chains | 2 |
Total formula weight | 49794.30 |
Authors | Zagotta, W.N.,Olivier, N.B.,Black, K.D.,Young, E.C.,Olson, R.,Gouaux, J.E. (deposition date: 2003-08-01, release date: 2003-09-09, Last modification date: 2011-07-13) |
Primary citation | Zagotta, W.N.,Olivier, N.B.,Black, K.D.,Young, E.C.,Olson, R.,Gouaux, J.E. Structural basis for modulation and agonist specificity of HCN pacemaker channels Nature, 425:200-205, 2003 Cited by PubMed: 12968185DOI: 10.1038/nature01922 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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