1PTU
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE-CONTAINING HEXA-PEPTIDE (DADEPYL-NH2)
Summary for 1PTU
Entry DOI | 10.2210/pdb1ptu/pdb |
Descriptor | PROTEIN TYROSINE PHOSPHATASE 1B, PHOSPHOTYROSINE-CONTAINING HEXA-PEPTIDE (3 entities in total) |
Functional Keywords | hydrolase, acetylation, phosphorylation, complex (hydrolase-peptide) complex, complex (hydrolase/peptide) |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P18031 |
Total number of polymer chains | 2 |
Total formula weight | 38166.30 |
Authors | Barford, D.,Jia, Z. (deposition date: 1995-04-21, release date: 1996-08-01, Last modification date: 2021-11-03) |
Primary citation | Jia, Z.,Barford, D.,Flint, A.J.,Tonks, N.K. Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B. Science, 268:1754-1758, 1995 Cited by PubMed: 7540771PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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