1PSA
STRUCTURE OF A PEPSIN(SLASH)RENIN INHIBITOR COMPLEX REVEALS A NOVEL CRYSTAL PACKING INDUCED BY MINOR CHEMICAL ALTERATIONS IN THE INHIBITOR
Summary for 1PSA
Entry DOI | 10.2210/pdb1psa/pdb |
Related PRD ID | PRD_000378 |
Descriptor | PEPSIN A, N-(ethoxycarbonyl)-L-leucyl-N-[(1R,2S,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-leucinamide (3 entities in total) |
Functional Keywords | acid proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Sus scrofa (pig) |
Cellular location | Secreted: P00791 |
Total number of polymer chains | 2 |
Total formula weight | 70110.54 |
Authors | Chen, L.,Abad-Zapatero, C. (deposition date: 1991-10-22, release date: 1994-01-31, Last modification date: 2017-11-29) |
Primary citation | Chen, L.,Erickson, J.W.,Rydel, T.J.,Park, C.H.,Neidhart, D.,Luly, J.,Abad-Zapatero, C. Structure of a pepsin/renin inhibitor complex reveals a novel crystal packing induced by minor chemical alterations in the inhibitor. Acta Crystallogr.,Sect.B, 48:476-488, 1992 Cited by PubMed: 1418819DOI: 10.1107/S0108768192001939 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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