1PQC

HUMAN LXR BETA HORMONE RECEPTOR COMPLEXED WITH T0901317

Summary for 1PQC

Entry DOI	10.2210/pdb1pqc/pdb
Related	1pq6 1pq9
Descriptor	Oxysterols receptor LXR-beta, N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE (3 entities in total)
Functional Keywords	lxrb+t0901317, transcription regulation
Biological source	Homo sapiens (human)
Cellular location	Nucleus (Potential): P55055
Total number of polymer chains	4
Total formula weight	118154.46
Authors	Farnegardh, M.,Bonn, T.,Sun, S.,Ljunggren, J.,Ahola, H.,Wilhelmsson, A.,Gustafsson, J.-A.,Carlquist, M. (deposition date: 2003-06-18, release date: 2003-09-09, Last modification date: 2024-04-03)
Primary citation	Farnegardh, M.,Bonn, T.,Sun, S.,Ljunggren, J.,Ahola, H.,Wilhelmsson, A.,Gustafsson, J.-A.,Carlquist, M. The three-dimensional structure of the liver X receptor beta reveals a flexible ligand-binding pocket that can accommodate fundamentally different ligands. J.Biol.Chem., 278:38821-38828, 2003 Cited by PubMed: 12819202 DOI: 10.1074/jbc.M304842200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation