1PQ6
HUMAN LXR BETA HORMONE RECEPTOR / GW3965 COMPLEX
Summary for 1PQ6
Entry DOI | 10.2210/pdb1pq6/pdb |
Descriptor | Oxysterols receptor LXR-beta, [3-(3-{[2-chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino}propoxy)phenyl]acetic acid, ISOPROPYL ALCOHOL, ... (4 entities in total) |
Functional Keywords | lxrb+kb043546/way207380/gw3965, transcription regulation |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (Potential): P55055 |
Total number of polymer chains | 4 |
Total formula weight | 118095.48 |
Authors | Farnegardh, M.,Bonn, T.,Sun, S.,Ljunggren, J.,Ahola, H.,Wilhelmsson, A.,Gustafsson, J.-A.,Carlquist, M. (deposition date: 2003-06-18, release date: 2003-09-09, Last modification date: 2024-04-03) |
Primary citation | Farnegardh, M.,Bonn, T.,Sun, S.,Ljunggren, J.,Ahola, H.,Wilhelmsson, A.,Gustafsson, J.-A.,Carlquist, M. The three-dimensional structure of the liver X receptor beta reveals a flexible ligand-binding pocket that can accommodate fundamentally different ligands. J.Biol.Chem., 278:38821-38828, 2003 Cited by PubMed: 12819202DOI: 10.1074/jbc.M304842200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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