1PKQ

Myelin Oligodendrocyte Glycoprotein-(8-18C5) Fab-complex

Summary for 1PKQ

• Entry DOI: 10.2210/pdb1pkq/pdb
• Related: 1PKO
• Descriptor: (8-18C5) chimeric Fab, light chain, (8-18C5) chimeric Fab, heavy chain, Myelin Oligodendrocyte Glycoprotein, ... (4 entities in total)
• Functional Keywords: autoantibody, multiple sclerosis, eae, immune system
• Biological source: Mus musculus (house mouse); More
• Cellular location: Membrane; Multi-pass membrane protein: Q63345
• Total number of polymer chains: 6
• Total formula weight: 137532.30

Authors

Breithaupt, C.,Schubart, A.,Zander, H.,Skerra, A.,Huber, R.,Linington, C.,Jacob, U. (deposition date: 2003-06-06, release date: 2003-07-15, Last modification date: 2011-07-13)

• Primary citation: Breithaupt, C.,Schubart, A.,Zander, H.,Skerra, A.,Huber, R.,Linington, C.,Jacob, U.; Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein; Proc.Natl.Acad.Sci.USA, 100:9446-9451, 2003; PubMed: 12874380; DOI: 10.1073/pnas.1133443100

Experimental method

X-RAY DIFFRACTION (3 Å)