1PKG

Structure of a c-Kit Kinase Product Complex

Summary for 1PKG

• Entry DOI: 10.2210/pdb1pkg/pdb
• Descriptor: c-kit protein, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: kinase, autophosphorylation, transactivation, transferase activator
• Biological source: Homo sapiens (human); More
• Cellular location: Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein. Isoform 3: Cytoplasm: P10721
• Total number of polymer chains: 2
• Total formula weight: 76009.39

Authors

Mol, C.D.,Lim, K.B.,Sridhar, V.,Zou, H.,Chien, E.Y.T.,Sang, B.-C.,Nowakowski, J.,Kassel, D.B.,Cronin, C.N.,McRee, D.E. (deposition date: 2003-06-05, release date: 2003-08-12, Last modification date: 2017-08-09)

• Primary citation: Mol, C.D.,Lim, K.B.,Sridhar, V.,Zou, H.,Chien, E.Y.T.,Sang, B.-C.,Nowakowski, J.,Kassel, D.B.,Cronin, C.N.,McRee, D.E.; Structure of a c-Kit Product Complex Reveals the Basis for Kinase Transactivation.; J.Biol.Chem., 278:31461-31464, 2003; PubMed: 12824176; DOI: 10.1074/jbc.C300186200

Experimental method

X-RAY DIFFRACTION (2.9 Å)