1PGR
2:2 COMPLEX OF G-CSF WITH ITS RECEPTOR
Summary for 1PGR
Entry DOI | 10.2210/pdb1pgr/pdb |
Descriptor | PROTEIN (GRANULOCYTE COLONY-STIMULATING FACTOR), PROTEIN (G-CSF RECEPTOR) (2 entities in total) |
Functional Keywords | class1 cytokine, hematopoietic receptor, signal transduction, cytokine |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P09919 Membrane; Single-pass type I membrane protein: P40223 |
Total number of polymer chains | 8 |
Total formula weight | 173108.10 |
Authors | Aritomi, M.,Kunishima, N.,Okamoto, T.,Kuroki, R.,Ota, Y.,Morikawa, K. (deposition date: 1999-03-08, release date: 2000-03-08, Last modification date: 2023-08-16) |
Primary citation | Aritomi, M.,Kunishima, N.,Okamoto, T.,Kuroki, R.,Ota, Y.,Morikawa, K. Atomic structure of the GCSF-receptor complex showing a new cytokine-receptor recognition scheme. Nature, 401:713-717, 1999 Cited by PubMed: 10537111DOI: 10.1038/44394 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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