1PGF
PROSTAGLANDIN H2 SYNTHASE-1 COMPLEXED WITH 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID (IODOINDOMETHACIN), CIS MODEL
Summary for 1PGF
| Entry DOI | 10.2210/pdb1pgf/pdb |
| Descriptor | PROSTAGLANDIN H2 SYNTHASE-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
| Functional Keywords | oxidoreductase, dioxygenase, peroxidase |
| Biological source | Ovis aries (sheep) |
| Total number of polymer chains | 2 |
| Total formula weight | 136194.71 |
| Authors | Loll, P.J.,Picot, D.,Garavito, R.M. (deposition date: 1995-12-02, release date: 1997-01-11, Last modification date: 2020-07-29) |
| Primary citation | Loll, P.J.,Picot, D.,Ekabo, O.,Garavito, R.M. Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site. Biochemistry, 35:7330-7340, 1996 Cited by PubMed: 8652509DOI: 10.1021/bi952776w PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (4.5 Å) |
Structure validation
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