1P7K
Crystal structure of an anti-ssDNA antigen-binding fragment (Fab) bound to 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid (HEPES)
Summary for 1P7K
Entry DOI | 10.2210/pdb1p7k/pdb |
Related | 1I8M |
Descriptor | antibody light chain FAB, antibody heavy chain FAB, SULFATE ION, ... (8 entities in total) |
Functional Keywords | fab, antibody, anti-dna antibody, autoantibody, lupus, hepes, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 99518.46 |
Authors | Schuermann, J.P.,Henzl, M.T.,Deutscher, S.L.,Tanner, J.J. (deposition date: 2003-05-02, release date: 2004-05-11, Last modification date: 2023-08-16) |
Primary citation | Schuermann, J.P.,Henzl, M.T.,Deutscher, S.L.,Tanner, J.J. Structure of an anti-DNA fab complexed with a non-DNA ligand provides insights into cross-reactivity and molecular mimicry. Proteins, 57:269-278, 2004 Cited by PubMed: 15340914DOI: 10.1002/prot.20200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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