1P7C
Crystal Structure of HSV1-TK complexed with TP5A
Summary for 1P7C
Entry DOI | 10.2210/pdb1p7c/pdb |
Related | 1P6X 1P72 1P73 1P75 |
Descriptor | Thymidine kinase, P1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE, SULFATE ION, ... (5 entities in total) |
Functional Keywords | p-loop, lid, bisubstrate inhibitor, transferase |
Biological source | Herpes simplex virus (type 1 / strain 17) |
Total number of polymer chains | 2 |
Total formula weight | 75640.86 |
Authors | Gardberg, A.,Shuvalova, L.,Monnerjahn, C.,Konrad, M.,Lavie, A. (deposition date: 2003-05-01, release date: 2003-11-04, Last modification date: 2023-08-16) |
Primary citation | Gardberg, A.,Shuvalova, L.,Monnerjahn, C.,Konrad, M.,Lavie, A. Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases. Structure, 11:1265-1277, 2003 Cited by PubMed: 14527394DOI: 10.1016/j.str.2003.09.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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