1P4Q

Solution structure of the CITED2 transactivation domain in complex with the p300 CH1 domain

Summary for 1P4Q

• Entry DOI: 10.2210/pdb1p4q/pdb
• Related: 1L3E
• Descriptor: Cbp/p300-interacting transactivator 2, E1A-associated protein p300, ZINC ION (3 entities in total)
• Functional Keywords: helix, protein-protein complex, transcription-transferase complex, transcription/transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : Q99967; Cytoplasm: Q09472
• Total number of polymer chains: 2
• Total formula weight: 17421.93

Authors

Freedman, S.J.,Sun, Z.-Y.J.,Kung, A.L.,France, D.S.,Wagner, G.,Eck, M.J. (deposition date: 2003-04-23, release date: 2003-07-01, Last modification date: 2017-02-01)

• Primary citation: Freedman, S.J.,Sun, Z.Y.,Kung, A.L.,France, D.S.,Wagner, G.,Eck, M.J.; Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2.; Nat.Struct.Biol., 10:504-512, 2003; PubMed: 12778114; DOI: 10.1038/nsb936

Experimental method

SOLUTION NMR