1P10

STRUCTURAL PLASTICITY AS A DETERMINANT OF ENZYME SPECIFICITY. CREATING BROADLY SPECIFIC PROTEASES

Summary for 1P10

Entry DOI	10.2210/pdb1p10/pdb
Related PRD ID	PRD_000316
Descriptor	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR, SULFATE ION, ... (4 entities in total)
Functional Keywords	serine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Lysobacter enzymogenes
Total number of polymer chains	2
Total formula weight	20381.40
Authors	Bone, R.,Agard, D.A. (deposition date: 1989-04-24, release date: 1990-04-15, Last modification date: 2012-12-12)
Primary citation	Bone, R.,Silen, J.L.,Agard, D.A. Structural plasticity broadens the specificity of an engineered protease. Nature, 339:191-195, 1989 Cited by PubMed: 2716847 DOI: 10.1038/339191a0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation