1ODX

HIV-1 Proteinase mutant A71T, V82A

Summary for 1ODX

• Entry DOI: 10.2210/pdb1odx/pdb
• Related: 1ODW
• Descriptor: HIV-1 PROTEASE, di-tert-butyl {iminobis[(2S,3S)-3-hydroxy-1-phenylbutane-4,2-diyl]}biscarbamate (3 entities in total)
• Functional Keywords: proteinase, retropepsin, retrovirus, hiv, aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human immunodeficiency virus 1 (HIV-1)
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P04585
• Total number of polymer chains: 2
• Total formula weight: 22155.15

Authors

Kervinen, J.,Thanki, N.,Zdanov, A.,Wlodawer, A. (deposition date: 1996-09-16, release date: 1997-04-01, Last modification date: 2024-02-14)

• Primary citation: Kervinen, J.,Thanki, N.,Zdanov, A.,Tino, J.,Barrish, J.,Lin, P.F.,Colonno, R.,Riccardi, K.,Samanta, H.,Wlodawer, A.; Structural Analysis of the Native and Drug-Resistant HIV-1 Proteinases Complexed with an Aminodiol Inhibitor; Protein Pept.Lett., 3:399-, 1996

Experimental method

X-RAY DIFFRACTION (2 Å)