1OB5

T. aquaticus elongation factor EF-Tu complexed with the antibiotic enacyloxin IIa, a GTP analog, and Phe-tRNA

Summary for 1OB5

Entry DOI	10.2210/pdb1ob5/pdb
Related	1B23 1EFT 1H1U 1IPM 1IPO 1IPQ 1IPR 1IPU 1L1U 1TTT 1TUI
Descriptor	ELONGATION FACTOR TU, TRANSFER-RNA, PHE, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (5 entities in total)
Functional Keywords	hydrolase, gtpase, translation elongation factor, transfer rna, gtp-binding, nucleotide-binding, protein biosynthesis
Biological source	THERMUS AQUATICUS More
Total number of polymer chains	6
Total formula weight	213955.73
Authors	Dahlberg, C.,Nielsen, R.C.,Parmeggiani, A.,Nyborg, J.,Nissen, P. (deposition date: 2003-01-24, release date: 2005-10-13, Last modification date: 2023-12-13)
Primary citation	Parmeggiani, A.,Krab, I.M.,Watanabe, T.,Nielsen, R.C.,Dahlberg, C.,Nyborg, J.,Nissen, P. Enacyloxin Iia Pinpoints a Binding Pocket of Elongation Factor TU for Development of Novel Antibiotics. J.Biol.Chem., 281:2893-, 2006 Cited by PubMed: 16257965 DOI: 10.1074/JBC.M505951200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation