1NX0
Structure of Calpain Domain 6 in Complex with Calpastatin DIC
Summary for 1NX0
Entry DOI | 10.2210/pdb1nx0/pdb |
Related | 1NX1 1NX2 1NX3 |
Descriptor | Calcium-dependent protease, small subunit, Calpastatin, Small molecule inhibitor, ... (5 entities in total) |
Functional Keywords | calcium binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Sus scrofa (pig) More |
Cellular location | Cytoplasm (By similarity): P04574 |
Total number of polymer chains | 5 |
Total formula weight | 42963.53 |
Authors | Todd, B.,Moore, D.,Deivanayagam, C.C.S.,Lin, G.-D.,Chattopadhyay, D.,Maki, M.,Wang, K.K.W.,Narayana, S.V.L. (deposition date: 2003-02-07, release date: 2003-08-19, Last modification date: 2024-02-14) |
Primary citation | Todd, B.,Moore, D.,Deivanayagam, C.C.S.,Lin, G.-D.,Chattopadhyay, D.,Maki, M.,Wang, K.K.W.,Narayana, S.V.L. A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor. J.Mol.Biol., 328:131-146, 2003 Cited by PubMed: 12684003DOI: 10.1016/S0022-2836(03)00274-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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