1NW9

STRUCTURE OF CASPASE-9 IN AN INHIBITORY COMPLEX WITH XIAP-BIR3

Summary for 1NW9

• Entry DOI: 10.2210/pdb1nw9/pdb
• Descriptor: Baculoviral IAP repeat-containing protein 4, caspase 9, apoptosis-related cysteine protease, ZINC ION (3 entities in total)
• Functional Keywords: caspase-9, xiap, caspase inhibition, caspase activation, dimerization, apoptosis
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 41866.65

Authors

Shiozaki, E.N.,Chai, J.,Rigotti, D.J.,Riedl, S.J.,Li, P.,Srinivasula, S.M.,Alnemri, E.S.,Fairman, R.,Shi, Y. (deposition date: 2003-02-05, release date: 2003-03-25, Last modification date: 2024-02-14)

• Primary citation: Shiozaki, E.N.,Chai, J.,Rigotti, D.J.,Riedl, S.J.,Li, P.,Srinivasula, S.M.,Alnemri, E.S.,Fairman, R.,Shi, Y.; Mechanism of XIAP-Mediated Inhibition of Caspase-9; Mol.Cell, 11:519-527, 2003; PubMed: 12620238; DOI: 10.1016/S1097-2765(03)00054-6

Experimental method

X-RAY DIFFRACTION (2.4 Å)