1N83
Crystal Structure of the complex between the Orphan Nuclear Hormone Receptor ROR(alpha)-LBD and Cholesterol
Summary for 1N83
Entry DOI | 10.2210/pdb1n83/pdb |
Descriptor | Nuclear receptor ROR-alpha, CHOLESTEROL (3 entities in total) |
Functional Keywords | three-layered alpha helical sandwich, receptor, transcription regulation, nuclear protein, dna binding, lipid binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P35398 |
Total number of polymer chains | 1 |
Total formula weight | 31900.93 |
Authors | Kallen, J.A.,Schlaeppi, J.M.,Bitsch, F.,Geisse, S.,Geiser, M.,Delhon, I.,Fournier, B. (deposition date: 2002-11-19, release date: 2002-12-11, Last modification date: 2024-02-14) |
Primary citation | Kallen, J.A.,Schlaeppi, J.M.,Bitsch, F.,Geisse, S.,Geiser, M.,Delhon, I.,Fournier, B. X-ray Structure of hROR(alpha) LBD at 1.63A: Structural and Functional data that Cholesterol or a Cholesterol derivative is the natural ligand of ROR(alpha) Structure, 10:1697-1702, 2002 Cited by PubMed: 12467577DOI: 10.1016/S0969-2126(02)00912-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.63 Å) |
Structure validation
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