1MZS

CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III WITH BOUND dichlorobenzyloxy-indole-carboxylic acid inhibitor

Summary for 1MZS

Entry DOI	10.2210/pdb1mzs/pdb
Related	1hn9 1hnd 1hnh 1hnj
Descriptor	3-oxoacyl-[acyl-carrier-protein] synthase III, PHOSPHATE ION, 1-(5-CARBOXYPENTYL)-5-(2,6-DICHLOROBENZYLOXY)-1H-INDOLE-2-CARBOXYLIC ACID, ... (4 entities in total)
Functional Keywords	fabh, transferase
Biological source	Escherichia coli
Cellular location	Cytoplasm : P0A6R0
Total number of polymer chains	1
Total formula weight	34140.31
Authors	Daines, R.A.,Pendrak, I.,Sham, K.,Van Aller, G.S.,Konstantinidis, A.K.,Lonsdale, J.T.,Janson, C.A.,Qui, X.,Brandt, M.,Silverman, C.,Head, M.S. (deposition date: 2002-10-09, release date: 2002-11-13, Last modification date: 2017-10-11)
Primary citation	Daines, R.A.,Pendrak, I.,Sham, K.,Van Aller, G.S.,Konstantinidis, A.K.,Lonsdale, J.T.,Janson, C.A.,Qiu, X.,Brandt, M.,Khandekar, S.S.,Silverman, C.,Head, M.S. First X-ray cocrystal structure of a bacterial FabH condensing enzyme and a small molecule inhibitor achieved using rational design and homology modeling J.Med.Chem., 46:5-8, 2003 Cited by PubMed: 12502353 DOI: 10.1021/jm025571b PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation