1M7N
Crystal Structure of Unactivated APO Insulin-like Growth Factor-1 Receptor Kinase Domain
Summary for 1M7N
Entry DOI | 10.2210/pdb1m7n/pdb |
Descriptor | Insulin-like growth factor I receptor (2 entities in total) |
Functional Keywords | transferase |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein: P08069 |
Total number of polymer chains | 2 |
Total formula weight | 73546.06 |
Authors | Munshi, S.,Kuo, L. (deposition date: 2002-07-22, release date: 2003-01-07, Last modification date: 2024-02-14) |
Primary citation | Munshi, S.,Kornienko, M.,Hall, D.L.,Reid, J.C.,Waxman, L.,Stirdivant, S.M.,Darke, P.L.,Kuo, L.C. Crystal structure of the Apo, unactivated insulin-like growth factor-1 receptor kinase. Implication for inhibitor specificity. J.Biol.Chem., 277:38797-38802, 2002 Cited by PubMed: 12138114DOI: 10.1074/jbc.M205580200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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