1LJM
DNA recognition is mediated by conformational transition and by DNA bending
Summary for 1LJM
| Entry DOI | 10.2210/pdb1ljm/pdb |
| Descriptor | RUNX1 transcription factor, CHLORIDE ION (3 entities in total) |
| Functional Keywords | immunoglobulin fold, beta-sandwich, transcription |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus: Q01196 |
| Total number of polymer chains | 2 |
| Total formula weight | 29336.61 |
| Authors | Bartfeld, D.,Shimon, L.,Couture, G.C.,Rabinovich, D.,Frolow, F.,Levanon, D.,Groner, Y.,Shakked, Z. (deposition date: 2002-04-22, release date: 2002-11-06, Last modification date: 2023-08-16) |
| Primary citation | Bartfeld, D.,Shimon, L.,Couture, G.,Rabinovich, D.,Frolow, F.,Levanon, D.,Groner, Y.,Shakked, Z. DNA Recognition by the RUNX1 Transcription Factor Is Mediated by an Allosteric Transition in the RUNT Domain and by DNA Bending. Structure, 10:1395-1407, Cited by PubMed: 12377125DOI: 10.1016/S0969-2126(02)00853-5 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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