1L8S
CARBOXYLIC ESTER HYDROLASE COMPLEX (DIMERIC PLA2 + LPC-ether + ACETATE + PHOSPHATE IONS)
Summary for 1L8S
Entry DOI | 10.2210/pdb1l8s/pdb |
Related | 1FX9 1FXF |
Descriptor | PHOSPHOLIPASE A2, MAJOR ISOENZYME, CALCIUM ION, SODIUM ION, ... (7 entities in total) |
Functional Keywords | hydrolase, enzyme, carboxylic ester hydrolase, dimer, paf hydrolysis products binding, phosphate binding |
Biological source | Sus scrofa (pig) |
Cellular location | Secreted: P00592 |
Total number of polymer chains | 2 |
Total formula weight | 29167.18 |
Authors | Pan, Y.H.,Bahnson, B.J. (deposition date: 2002-03-21, release date: 2002-12-25, Last modification date: 2018-01-31) |
Primary citation | Pan, Y.H.,Yu, B.-Z.,Berg, O.G.,Jain, M.K.,Bahnson, B.J. Crystal structure of phospholipase A2 Complex with the Hydrolysis Products of Platelet Activating Factor: Equilibrium Binding of Fatty Acid and Lysophospholipid-ether at the Active Site may be Mutually Exclusive Biochemistry, 41:14790-14800, 2002 Cited by PubMed: 12475227DOI: 10.1021/bi026922r PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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